Clinical trial for experimental Ebola drug publishes results
Rapid assessment approach finds TKM-130803 ineffective at the dose given. Results of the Wellcome Trust funded trial of the experimental anti-Ebola drug TKM-130803 have been published April 19 in...
View ArticleInfectious outbreaks must be combatted strategically, Dartmouth-HHS experts...
New funding is not enough to guarantee success against emerging infectious diseases around the world.
View ArticleCellphone-sized device quickly detects the Ebola virus
The worst of the recent Ebola epidemic is over, but the threat of future outbreaks lingers.
View ArticleEbola virus genome provides clues to repeated disease 'flare-ups' in Western...
Ebola virus samples taken from patients in Liberia in June 2015 are strikingly similar in their genetic makeup to other Ebola virus sequences from Western Africa, according to research published...
View ArticleCancer drug may treat sepsis, other uncontrollable immune responses to...
NIH-funded study reveals topoisomerase 1 inhibitors suppress inflammation in mice.
View ArticleEbola vaccine: Promising phase I trials
"The results for tolerability, safety, and the immune response to the vaccine candidate are very promising," explains Prof Marylyn Addo.
View ArticleTowards a pan-ebolavirus treatment
In 2014, the alarm for the Zaire Ebola virus was sounded around the world - but there are other deadly ebolaviruses that cause identical symptoms, and they have even fewer treatment options.
View ArticleReview of Ebola response provides context for future infection control...
National recommendations and strategies are needed to help hospitals prepare for potential Ebola cases and other emerging infectious diseases.
View ArticleNew study sheds light on how some survive Ebola
A first-of-its-kind Ebola study yields clues to how some people are able to survive the deadly virus and suggests possible avenues for treatments that could save more lives.
View ArticleTSRI scientists pinpoint Ebola's weak spots
Scientists at The Scripps Research Institute (TSRI) now have a high-resolution view of exactly how the experimental therapy ZMapp targets Ebola virus.
View ArticleHow antiviral antibodies become part of immune memory
Weapons production first, research later. During wartime, governments follow these priorities, and so does the immune system.
View ArticleNew model could help improve prediction of outbreaks of Ebola and Lassa fever
Potential outbreaks of diseases such as Ebola and Lassa fever may be more accurately predicted thanks to a new mathematical model developed by researchers at the University of Cambridge.
View ArticleEbola adapted to better infect humans during 2013-2016 epidemic
Researchers have identified mutations in Ebola virus that emerged during the 2013-2016 Ebola virus epidemic in West Africa that increased the ability of the virus to infect human cells, two...
View ArticleSymptom-free Ebola infections detected in West Africa
Between 2013 and 2016, tens of thousands of people in West Africa contracted Ebola virus disease, making the epidemic the largest and longest on record.
View ArticlePotential evidence of lung-specific Ebola infection found in recovering patient
Scientists have found potential evidence of Ebola virus replication in the lungs of a person recovering from infection, according to new research published in PLOS Pathogens.
View ArticleBlood test can predict life or death outcome for patients with Ebola virus...
Scientists have identified a 'molecular barcode' in the blood of patients with Ebola virus disease that can predict whether they are likely to survive or die from the viral infection.
View ArticleNew scoring system predicts Ebola severity
While Ebola virus disease (EVD) is notorious for being one of the world's most deadly infections, it actually has a wide range of outcomes, where asymptomatic presentation may be as common as...
View ArticleDisease "superspreaders" were driving cause of 2014 Ebola epidemic
A new study about the overwhelming importance of "superspreaders" in some infectious disease epidemics has shown that in the catastrophic 2014-15 Ebola epidemic in West Africa, about 3 percent of...
View ArticleEbola vaccines provide immune responses after 1 year
Immune responses to Ebola vaccines at one year after vaccination are examined in a new study appearing in JAMA.
View ArticleNew animal infectious disease modeling study has implications for humans
A new study published in the Proceedings of the National Academy of Sciences, will help answer a fundamental disease ecology question about the spread of infectious diseases such as Ebola and...
View ArticleNIH study of Ebola patient traces disease progression and recovery
Analysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health in 2015 found changes in antiviral and immune response genes that...
View ArticleLessons from Ebola: New approach improves disease outbreak management
A new approach to information gathering could allow scientists to quickly identify the most effective way to manage a disease outbreak, an advance that could save lives.
View ArticleEbola vaccine developed in Canada shows promising results
A phase 1 randomized controlled trial has found an Ebola virus disease (EVD) vaccine, developed in Canada, was well-tolerated with no safety concerns, and high antibodies were present in participants...
View ArticleCan bats 'tell us' when and where Ebola will strike next?
A new study suggests that we may be able to predict exactly when and where Ebola will next break out if we look to bats' migratory patterns.
View ArticleWhat causes coffee ground vomitus?
Coffee ground vomitus is dark-colored vomit that has blood in it. Possible causes include gastric ulcers, gastritis, liver disease, and cancer. Anyone who vomits blood should seek immediate medical...
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